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Osei SP, Akomaning E, Florut TF, Sodhi M, Lacy BE, Aldhaleei WA, et al

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May promote increased lean body mass, reduced fat mass, and improved body composition consistent with GH/IGF-1 axis activation [4] [9]

Retatrutide (5mg-10mg), Triple Incretin Receptor Agonist Engineered Engagement of GLP-1, GIP, and Glucagon Receptors Introduction Engineered Engagement of GLP-1, GIP, and Glucagon Receptors Retatrutide is a synthetic 39-residue peptide engineered as a balanced agonist of three distinct class B G protein-coupled receptors: the glucagon-like peptide-1 receptor (GLP-1R), the glucose-dependent insulinotropic polypeptide receptor (GIPR), and the glucagon receptor (GCGR)