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When you lose weight, your body naturally adapts: Metabolism can slow Hunger hormones may increase Energy expenditure changes Your body attempts to defend its previous weight Research consistently shows that plateaus are extremely common during weight loss treatment, including with GLP-1 medications

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ReconMap: an interactive visualization of human metabolism

Researchers planning new experimental work should consult the most recent literature beyond the citations provided here, since the research record continues to expand and the contemporary research-context framing benefits from inclusion of the most current findings