doi: 10.3389/fnut.2022.1082097 Received 27 October 2022 Accepted 21 December 2022 Published 10 January 2023 Volume 9 - 2022 Edited by Sandro Massao Hirabara, Universidade Cruzeiro Do Sul, Brazil Reviewed by Elisabetta Camajani, Sapienza University of Rome, Italy
Over three to twelve months of well-managed peptide therapy, patients commonly see: Improved growth hormone signaling and rising IGF-1 levels A more favorable cortisol curve with less stress-related disruption Better fasting insulin, blood sugar control, and A1C Sex hormones stabilizing relative to age and life stage Enhanced sleep quality, energy, and cognitive function Reduced body fat and preserved or increased muscle mass Patients may see improvements within weeks while full results can take months
AGE, advanced glycation end product
A comparative study conducted between GLP-1RA + Metformin in contrast to cyproterone acetate/ethinylestradiol + Metformin in overweight PCOS women, conducted over a period of 12 weeks, implied that GLP-1 RA+Metformin was superior in reducing the waist circumferences as well as preserving blood sugar levels by improved HbA1c levels and regulating menstrual cycle
