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San Diego, CA: Academic Press (2009)

Banks et al

NNMT upregulation also elevates homocysteine levels, activating pro-inflammatory and pro-oxidative cascades (TLR4-NF-B and STAT3-IL-1 pathways) linked to atherosclerosis, heart failure, and coronary heart disease

I have to say, I started taking L-glutamine years ago in times when I was working a lot and not sleeping enough because someone told me it would help me not get sick