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The practical cost comparison: | Medication | Monthly Cash Price | Typical Insurance Copay | Duration | |---|---|---|---| | Generic lisdexamfetamine | $30 to $80 | $10 to $35 | 12 to 13 hours | | Generic mixed amphetamine salts XR | $15 to $50 | $5 to $25 | 10 to 12 hours | | Generic methylphenidate ER (osmotic) | $20 to $45 | $5 to $25 | 10 to 12 hours | | Brand Vyvanse | $350 to $450 | $40 to $75+ | 12 to 13 hours | | Brand Concerta | $300 to $400 | $35 to $60 | 10 to 12 hours | | Brand Adderall XR | $280 to $380 | $35 to $60 | 10 to 12 hours | Non-Stimulant Alternatives and Their Costs Some patients cannot tolerate stimulants or have contraindications such as uncontrolled hypertension, cardiac arrhythmias, or active substance use disorders

The goal is to help patients understand how weight, metabolism, hormones, inflammation, muscle, and long-term health fit together