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It is also heavily studied for its role in inflammation regulation and the remodeling of the extracellular matrix

Consequently, we analyzed three sets of publicly available ADR or MES gene signatures (Supplementary data S1): the Integrated (Int) ADR signature and Int MES signature 12 , which integrate six established signatures from different sources (cells lines, PDXs, and patient tumors)

Chilling injury resulting from LT stress is associated with disparity between making and elimination of ROS

Mechanistic analysis revealed that AR directly promoted the transcription of miR-221, which in turn suppressed IGF-1 expression, leading to the inactivation of the MAPK pathway in DPCs and the PI3K/AKT pathway in DSCs