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In clinical trials of oral Rybelsus (the previous formulation of the Ozempic pill) in people with type 2 diabetes, people lost around 58 pounds (about 2.5%4% of their baseline weight) after 26 weeks and the higher the dose of the medication, the more weight they lost

In general, however, it is recommended to receive regular injections every month for maximum effectiveness and the best benefits for well-being

While effective during treatment, their long-term benefit hinges on whether weight loss persists after discontinuation