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Contribution margin per unit = Selling price Variable cost per unit = $4,000 $1,000 = $3,000 Breakeven = Fixed Costs Contribution margin per unit = $4,800,000 $3,000 = 1,600 units 1b

In accordance with findings based on phase 3 semaglutide data investigating covariate effects on CL/ F [6], body weight was found to be the only important covariate with respect to CL and, hence, average semaglutide concentrations under steady-state conditions with 90% CIs outside the equivalence interval

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