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In individuals with type 2 diabetes and NAFLD, macrovascular complications are a leading cause of morbidity and mortality [25]

Data availability about the pathophysiological processes involved in triggering NIHL has allowed researchers to use compounds, that could act as effective therapies, by targeting specific mechanisms such as the excess generation of free radicals and blood flow restriction to the cochlea

Semaglutide was shown in trials to significantly lower blood sugar levels and cut body weight by an average of 15%

Similarly, NICE Technology Appraisal 664 recommends liraglutide 3.0 mg (Saxenda) with more restrictive criteria, including a BMI threshold of 35 kg/m (or 32.5 kg/m in certain ethnic groups) plus prediabetes and high cardiovascular risk