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The 2 mL volume produces concentrations (2.5, 5, 10, 15 mg/mL) that put common doses on multiples of 10 units

A deficiency can result in severe neurological problems, including memory loss, depression, and significant nerve damage

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Preliminary cardiac studies have also explored the use of recombinant human T4 following severe ST-segment elevation myocardial infarctions (STEMI), with early pilot data suggesting the intervention is feasible, safe, and potentially capable of improving left ventricular ejection fractions by more than 50% in specific cohorts six months post-infarction