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One commenter believed that CMS packaging policies may encourage efficiencies and help lower costs, but they believed that packaging policies could penalize hospitals that provide complex care to sicker patients

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Table 13: Number (%) of Patients with 3 or More Step Progression on ETDRS Scale at Endpoint The ORIGIN Study Of Major Cardiovascular Outcomes In Patients With Established CV Disease Or CV Risk Factors The Outcome Reduction with Initial Glargine Intervention study (i.e., ORIGIN) was an open-label, randomized, 2-by-2, factorial design study

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