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Daily Value*

Neurotrophic benefits Calm hyperexcitable nerve endings, reduce aberrant firing, improve local pain signaling, and enable stable motor recruitment patterns Tissue regeneration and remodeling Five stages: Homing signal (paracrine signaling) Homeostatic signals summon endogenous progenitors from marrow, adipose, and other reservoirs

Mitochondria-targeted antioxidants hold great promising and may serve as a useful approach for the alleviation of age-related diseases

(2017), vitamin E supplementation alone impaired sustained attention in individuals with high baseline PUFA levels, likely due to excessive increases in serum -tocopherol which may have acted as a pro-oxidant in an already lipid-rich environment, thereby disrupting redox balance and contributing to cognitive decline [59]