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At the same time, compelling cardiovascular outcomes data will be equally critical for commercial success to demonstrate value to health systems: Novos SELECT trial read out in 2023, demonstrating the impact of Wegovy-induced weight loss was a statistically significant 20% reduction in a composite endpoint consisting of cardiovascular death, non-fatal myocardial infarction, or non-fatal stroke in 17,604 overweight or obese patients with prior cardiovascular disease