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Similarly, Wu and his team [193] combined double-click stapling groups with photoaffinity labeling within a single linker, and then added a protected alkyne handle to incorporate a biotin moiety for pull-down assays (Figure 12F)

Although most proteins required for mitochondrial function are encoded by nuclear DNA and synthesised by cytoplasmic ribosomes for targeted transport [30], regular respiratory chain activity requires structurally intact and functionally normal mitochondrial genes [31]

however, NGAL production rises in response to renal tubular epithelial cell injury

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