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Report warning signs immediately: unilateral leg swelling or pain, chest discomfort, unexplained shortness of breath, or calf tenderness

Mechanism of Action The chemical structure of tesamorelin is almost identical to the hypothalamic peptide growth hormone-releasing hormone (GHRH), which occurs naturally in the body

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The mechanism by which GLP-1 RAs potentially increase suicide or suicide attempts is unclear but may involve an overactivation of the hypothalamic-pituitary-adrenal (HPA) axis [7], rapid weight loss [8], and reduced expression of brain-derived neurotrophic factor which may link weight changes to heightened anxiety and suicidal risk [9]