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Moreover, an up-regulated TNF- protein level and decreased SYP, PSD95 and BDNF protein level was observed in the hippocampus of ethanol-exposed APP/PS1 mice, while the altered protein level was partially restored after being treated with NAC (Fig

Nonexpression of GLP-1R is common in advanced pancreatic tumors with lymphatic metastasis and is associated with poor prognosis, suggesting that GLP-1R may inhibit tumorigenesis and metastasis of human pancreatic cancer cells both in vitro and in vivo

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[223] [224] The full profile of amphetamine's short-term drug effects in humans is mostly derived through increased cellular communication or neurotransmission of dopamine, [39] serotonin, [39] norepinephrine, [39] epinephrine, [192] histamine, [192] CART peptides, [22] [218] endogenous opioids, [225] [226] [227] adrenocorticotropic hormone, [228] [229] corticosteroids, [228] [229] and glutamate, [197] [214] which it affects through interactions with CART, 5-HT 1A , EAAT3, TAAR1, VMAT1, VMAT2, and possibly other biological targets