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It is likely a different substance altogether, but even if it is a close mimic, the substance could be contaminated, impure, or of an unknown strength. Apovian echoes this: Phase 3 trials arent even finished yet youre really taking your life into your own hands

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Noom, Calibrate, and Embla say there is preliminary data to support their contention that many people can maintain weight loss through exercise and diet after stopping the medications (though some of the doctors Fortune spoke with were skeptical of those studies)

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