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Mean smokers MDA level of 2.06 1.39 nmol/mL was not significantly different compared with mean nonsmokers MDA level (1.32 0.90 nmol/mL) (p=0.092)

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The same study also noted significant oiliness reduction and texture smoothing in 70-80% of participants, which supports the idea that combined exfoliation can work, but also raises a real concern about irritation when people try to recreate that effect without a precise formulation