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Zhang L, Zhang L, Li L, Hlscher C (2018) Neuroprotective effects of the novel GLP-1 long acting analogue semaglutide in the MPTP Parkinsons disease mouse model

Others exclude them entirely or require prior authorization demonstrating failed conservative treatments

10.7150/thno.45192 20 FanY.LiuK.WangQ.RuanY.YeW.ZhangY

Together, these data suggested that activating GLP-1R alleviated glycolysis, at least partially by the suppression of PFKFB3-driven glycolysis, and attenuated lactate-mediated histone lactylation, which in turn suppressed the transcription of profibrotic genes in TGF-1 + IL-1-challenged fibroblasts