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Weight loss is minimal, often 1-2 pounds over the first month, primarily from reduced food intake rather than dramatic appetite changes
SARS-CoV-2 infection of Calu-3 cells caused a strong induction of the antiviral interferon-stimulated gene (ISG) signature, including several antiviral effectors, such as cGAS, Mx1, IFIT, IFIH, IFI16, IFI44, OAS, and ISG15, pathways of vesicular transport, tight junctions (KIF5A/B/C, OSBPL2, CLTCL1, and ARHGAP17) and ubiquitin modification (UBE2L3/5), as well as reprogramming of host metabolism, transcription and translation
This study defined a key step in chemokine-triggered signalling in T cells giving molecular detail of the regulation of talin activity
Bertler A et al (1966): The localization of monoaminergic blood-brain barrier mechanisms
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