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ectopic and eutopic endometrium tissue samples were taken from each participant during laparoscopy The samples underwent peptide extraction, peptide purification, peptide desalting and TMT labeling Analyses were done by Liquid chromatography (LC)-tandem mass spectrometry techniques Bioinformatics was used to determine the peptide-protein precursor functions Highly differentiated endometrial stromal cells (ESC) obtained and cultured, then subject to wound healing assays, to illuminate migration patterns in the presence of the above peptides Transwell assays were used to determine the invasive properties of some cells The data was subject to statistical analysis

25,26 Furthermore, a polymorphism of the DHFR enzyme resulting in a 19bp deletion within the site of a key regulatory sequence has been theorized to exhibit negative effects on the expression and activity of this enzyme

Consistent results have been observed in both patients with depression and those with IBD (344346)