In AWARD-10 [31], a 24-week, randomized, double-blind, placebo-controlled trial evaluating once-weekly dulaglutide (administered at either 1.5 or 0.75 mg) as add-on therapy to SGLT2is in a total of 424 patients with inadequately controlled T2DM, only one episode of severe hypoglycemia was reported throughout the study, in a patient treated with dulaglutide 0.75 mg, confirming the very low incidence of serious hypoglycemia with GLP-1RAs in combination with SGLT2is [31]
While genetic data does not predict exact medication response or injection tolerance, understanding your individual genetic profile may help your provider tailor preparation strategies and dosing approaches that align with your physiological predispositions
You are already taking other weight-loss medications
Astaxanthin may help reduce oxidative stress at the cellular level, lutein is concentrated in the retina and may help filter high-energy blue light to support normal vision, and L-glutathione supports intracellular antioxidant balance and overall cellular protection
