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Apoptosis Initiation: Once liberated, p53 translocates to the mitochondria and activates BAX/BAK, triggering intrinsic apoptosis (cell death) specifically in the senescent cell

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Despite their advantages, peptides face ongoing limitations including stability challenges, delivery constraints, and higher costs compared to traditional pharmaceuticals

Promoting angiogenesis: BPC-157 stimulates the expression of vascular endothelial growth factor, promoting the formation of new blood vessels