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Conclusion Long-term randomized placebo-controlled trials with larger sample sizes are needed to provide stronger evidence on the long-term efficacy and safety of semaglutide for obesity treatment in PWS as well as explore the potential synergistic effects of GLP-1 RA treatment combined with other therapeutic interventions

Adapting Lifestyle and Behavioral Practices for Relief Beyond dietary changes, lifestyle and behavioral practices play a crucial role in mitigating nausea