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The risk of hyperglycemia is disproportionately higher among patients with either diabetes or prediabetes

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MK-677 has shown promise in addressing muscle loss and hormonal decline, particularly in older adults and those with GH deficiency. Smith et al., The Journal of Clinical Endocrinology & Metabolism Key Benefits of MK-677 for Muscle Growth 1

For adults with comorbid insomnia, there is a small amount of evidence that it might be helpful, but much more research is needed (Andrade et al., 2001)