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d HR+/HER2-, hormone receptor positive/human epidermal growth factor receptor negative

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These effects are studied as part of integrated endocrine signaling networks rather than as isolated outcomes, supporting investigation of how coordinated receptor activation shapes cellular responses in controlled experimental systems

Search Strategy A systematic search following guidelines established by the Preferred Reporting Items for Systematic Reviews and MetaAnalyses (PRISMA) was performed in PubMed, Embase and Cochrane Library for studies until December 8, 2024