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Despite inherent limitations of observational data and potential for residual confounding, the results from these observational analyses support, in line with RCT findings, combining SGLT2is and GLP-1RAs to reduce cardiovascular events in patients with diabetes in routine clinical care [12, 23, 43, 63]

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Pyrroloquinoline quinone attenuates fat accumulation in obese mice fed with a high-fat diet, daphnia magna supplied with a high amount of food, and 3T3-L1 adipocytes