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Alpha lipoic acid regenerates vitamins C and E, increases tissue levels of glutathione, and helps maintain the proper ratio of reduced to oxidized coenzyme Q10 in the mitochondria

A significant decrease in the levels of IL-10 was also observed in the plasma samples ( Figure 5G ) at 3-months post-L-GSH supplementation

Yet, overproduction of reactive oxygen species (ROS), induced by environmental toxins, inflammation, or mitochondrial dysfunction, overwhelms the cellular antioxidant defense system, resulting in oxidative stress [27]

In functional medicine, those clues matter because they point toward systems that change over time and might be modifiable