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Sources: Institute of Medicine, Food and Nutrition Board, National Academies of Science, Dietary Reference Intakes (DRI): Recommended Dietary Allowances and Adequate Intakes , USA 2018, Mustafa Vakur Bor, Kristina M von Castel-Roberts, Gail PA Kauwell, Sally P Stabler, Robert H Allen, David R Maneval, Lynn B Bailey Ebba Nexo Daily intake of 4 to 7 g dietary vitamin B-12 is associated with steady concentrations of vitamin B-12related biomarkers in a healthy young population Am J Clin Nutr 2010 91: 3 571-577

DOI: 10.1016/j.lfs.2012.01.003 87

Pramlintide and T1DM Pramlintide treatment in T1DM might benefit highly motivated patients sub-optimally treated with basal-bolus insulin therapy or patients on insulin pump therapy with weight gain despite all recommended lifestyle changes [70,77]