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Vitamin C-induced decomposition of lipid hydroperoxides to endogenous genotoxins

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Methods for 9-[2-(Diethylphosphonomethoxy)ethyl]adenine Synthesis In an embodiment, synthesis of 9-[2-(diethylphosphonomethoxy)-ethyl]adenine, shown in Diagram A, Step 3, is described as follows

Redox disequilibrium is associated with pathology of cardiovascular [20], diabetes and cataracts [19] [21] in our previous studies, where erythrocyte GPX activity was found to be a sensitive marker of oxidative stress