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Prognostic and mechanistic potential of progesterone sulfates in intrahepatic cholestasis of pregnancy and pruritus gravidarum
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They were initially defined as secretory GPX, but later studies have shown that both enzymes are localized to the endoplasmic reticulum and are necessary enzymes involved in the oxidative folding of endoplasmic reticulum proteins (Figure 8)
Once injected (or swallowed), they saturate your system with GLP-1-like activity at levels far higher, steadier, and longer-lasting than what your body naturally experiences
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