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Sirtuin-3, a nuclear protein translocated to the mitochondrial matrix upon oxidative stress (Klotz et al., 2015), plays an important role in mitochondrial bioenergetics and defense to oxidative stress

Last reviewed: July 21, 2026 Last updated: July 21, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

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