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The slower release profile allows for once-daily dosing without the plasma concentration spikes and crashes associated with IM bolus delivery

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Oct 2024: A multi-society guidance (ASA, AGA, ASMBS, SAGES, etc.) concluded most patients can continue GLP-1s before elective surgery/endoscopy, with risk-stratified adjustments like liquid diet day prior, point-of-care gastric ultrasound, or brief hold for high-risk situations like active GI symptoms or rapid dose escalation